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However, research on this interaction is inconsistent and controversial Like, if you should continue with your birth control pills this month or skip them and use condoms. If you’re taking rifampicin, it’s essential to use a secondary, non-hormonal method of contraception during the course of antibiotics and for seven days afterward. Oral contraceptives should not be relied upon for birth control while taking rifampin. A second method of contraception is necessary, and it is crucial to inform the patient of the chance for an interaction.